Deriva-Bpo Gel is a combination of two medicines: Adapalene and Benzoyl Peroxide, which treats acne (pimples). Adapalene is a form of vitamin A and Benzoyl Peroxide is a keratolytic medicine. Together, they prevent accumulation of the sebum (skin’s natural oil), unblock the pores and allow natural exfoliation of the outer layers of skin. Benzoyl Peroxide additionally penetrates into the skin and kills acne-causing bacteria.